对389名大学生施测社会支持量表、自尊量表、社会与感情孤独量表及主观幸福感量表，以探讨孤独和自尊在社会支持与主观幸福感的关系中的作用。结果表明：（1）主观幸福感与社会支持、自尊、孤独呈显著相关。（2）路径分析表明，自尊、孤独分别在社会支持与主观幸福感之间起显著的中介作用。社会支持→自尊→孤独→主观幸福感的显著路径表明，这些变量间存在更为复杂的关系。这些结果对于大学生心理健康教育具有重要的意义。

To explore the relationships among social support, loneliness, self-esteem and subjective well-being, 389 college students was asked to complete the social support rating scale, the emotional and social loneliness scale, the self-esteem scale and the satisfaction with life scale. The result showed that (1) significant correlation was found between social support, loneliness, self-esteem and subjective well-being. (2) Path analysis showed a full mediation effect of loneliness and self-esteem between subjective well-being. And a significant path from social support through self-esteem and loneliness to life satisfaction suggested more complicated relations among the variables. These findings play a significant role in college students’ psychological health education.