The present study unpacked the black box of underlying mechanism of transformational leadership influences on employees’ job performance and job satisfaction. The participants were 426 employees and managers from many industries (such as government, manufacturing, banking, etc.). SPSS13.0 and Lisrel 8.7 are adopted to perform a series of statistical analysis, including reliability analysis、Confirmative Factor Analysis(CFA)、correlation analysis as well as hierarchical linear regression analysis. Especially, we followed Wen, Zhang and Hou (2006)’s procedures and tested the mediated moderation effect. The results showed that: (1) The relationship between transformational leadership and job performance、job satisfaction are both partially mediated by self-efficacy, after controlling for variables such as age, gender, and organization tenure; (2) As a moderator, core job characteristics strengthened the positive relation between transformational leadership and job performance. Such moderation effect was mediated by the self-efficacy of employees. At the end of this study, the theory contribution and practical implications of this research were discussed.