Nowadays social network sites (SNS) have been popular all over the world and already integrated into people’s daily life. Individuals used social network sites out of lots of motivations such as entertainment, needs of connecting and belonging, maintaining and deepening relationships as well as self-presentation. Self-presentation which was also called impression management or impression regulation referred to that one controlled the content of the information and the way it was presented in order to affect the formation and change of their impressions on others. Self-presentation was quite a common phenomenon in interpersonal interactions in offline life. With the development of internet, more and more individuals began to present themselves in cyberspace which provided them a relatively safe environment. And social network sites were considered as the ideal platform of self-presentation for people could engage in self-presentation through social network sites profile construction, status updates, photo album management, message-posting and so on. Researchers revealed that as most social network sites friends were offline friends who knew or could know the presenter easily in real life, individuals would have to present true information about themselves in case that others thought they were dishonest. Therefore, honest self-presentation was one of the main strategies that people adopted when self-presenting. Existing researches also indicated that SNS honest self-presentation had significant effect on life satisfaction, and online positive feedback as well as general self-concept might play important roles in between SNS honest self-presentation and life satisfaction. To investigate the relationship among SNS self-presentation, online positive feedback general self-concept and life satisfaction, a survey research method was adopted in which SNS Honest Self-presentation Questionnaire, SNS Positive Feedback Questionnaire, General Self-concept Questionnaire as well as Satisfaction with Life Scale were administered to 554 middle and high school students. Data were collected and analyzed with SPSS 17.0，and the bias-corrected percentile Bootstrap method was used to analyze the chain mediating roles of online positive feedback and general self-concept in between SNS honest self-presentation and adolescents’ life satisfaction. The results indicated: (1) the relationships between each pair of SNS honest self-presentation, online positive feedback, general self-concept as well as life satisfaction were significantly positive; SNS honest self-presentation had no direct effect on life satisfaction, but could significantly predict online positive feedback and general self-concept; online positive feedback could significantly predict general self-concept; both online positive feedback and general self-concept could significantly predict life satisfaction. (2) SNS honest self-presentation affected adolescents’ life satisfaction through three indirect paths: through the mediating role of online positive feedback; through the mediating role of general self-concept; through the chain mediating role of both online positive feedback and general self-concept. These findings highlighted the complex nature of association between honest self-presentation in online social network sites and adolescent’s life satisfaction. Honest self-presentation in online social network sites influenced life satisfaction through online positive feedback and general self-concept. Individuals who presented themselves with honest self-presentation strategy on social network sites would get more positive feedback and have positive general self-concept, and finally have higher level of life satisfaction.