Interpersonal curiosity, which is the desire for new information about people, is of great importance in social interaction and human relationship. We aim to examine how an individual’s current social circumstance and gender influence interpersonal curiosity. Participants were asked to complete a two-person gambling task with an assistant unknown to them. Results demonstrate that (1) when people’s current circumstances are better than those of others under the same situation, the degree of their interpersonal curiosity is stronger; and (2) females are more curious about other people than are males when their exploratory behaviors are free. This study is an initial foray into providing comprehensive knowledge on interpersonal curiosity.