The previous studies show that the perceived behavioral control (PBC) towards quitting smoking would be weakened by the increased nicotine dependence among daily smokers. However, there is little research examining the effects of social environmental factors on PBC towards quitting among the Chinese male daily smokers. Guided by the theories of Buffering Effect Model, the negative effect of nicotine dependence on PBC towards quitting may be buffered by the positive social support for quitting smoking from others. Additionally, both of the social support for quitting smoking and complaint of smoking from others are frequently perceived by smokers. However, little is known about the influence of complaint of smoking from others on the PBC towards quitting smoking. The present study aims to examine the interactive moderating effect of the perceived social support for quitting smoking and complaint of smoking from others on the relationship between nicotine dependence and PBC towards quitting among smokers. A sample of 326 Chinese male current daily smokers were recruited to complete several self-report questionnaires, including Fagerstr?m Test for Nicotine Dependence, Scale of PBC towards Smoking Cessation, and the sub-scales of perceived social support for quitting smoking and complaint of smoking from others from the Partner Interaction Questionnaire. The moderation analysis were conducted by using PROCESS macro for SPSS. The results show that: (1) The PBC towards quitting smoking is significantly and negatively predicted by nicotine dependence. (2) The interactive moderating effect of perceived social support for quitting smoking and complaints of smoking from others on the relationship between nicotine dependence and PBC towards quitting smoking is significant. As for the smokers who perceive less complaint of smoking and perceive less social support for quitting from others, as well as for the smokers who perceive more complaint of smoking and perceive more social support for quitting from others, the relationship between nicotine dependence and PBC towards quitting smoking is significant. As for the smokers who perceive less complaint of smoking and perceived more social support for quitting from others, as well as for the smokers who perceive more complaint of smoking and perceive less social support for quitting from others, the relationship between nicotine dependence and PBC towards quitting is not significant. The findings are consistent with the hypothesis of Buffering Effect Model and suggest that the social support for quitting smoking could function as a buffer which buffering the negative influence of nicotine dependence on PBC towards quitting smoking. Moreover, the current findings furtherly indicate that the perceptions of social support for quitting and complaint of smoking from others are co-existed and antagonistic for Chinese male daily smokers. The buffering function of social support for quitting is moderated by the complaint of smoking from others. The positive function of social support for quitting is shown when the smokers perceive lower degree of complaints of smoking from others. Further studies should distinguish the different social members’ support and complaint and examine the different effects of them on PBC towards quitting smoking among the Chinese male daily smokers.